Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1976-05-24
1977-11-08
Drezin, Norman A.
Drug, bio-affecting and body treating compositions
Dentifrices
424317, A61K 716
Patent
active
040576213
ABSTRACT:
A composition and method of treatment for desensitizing hypersensitive dentin and cementum capable of effective results specially in one-treatment application. The essential ingredient or compound of the desensitizing composition is an alkali metal or ammonium oxalate where this salt may be mono- or di-substituted. The hydrogen or mono-substituted salts are preferred due to their lower pH which renders them more efficient in the protocol of this invention. These oxalates may be used effectively in the range 0.5% by weight to aqueous solution saturation. However, a range of 2.0% to solution saturation is much preferred due to the practice of the invention as a single-treatment agent. Furthermore, saturated solutions of the oxalates are most preferred also due to greater efficiency. The compositions may be used in aqueous solutions and as non-toxic paste with conventional fillers and excipients. In the paste form, the oxalate is preferred in a weight percent basis of 2-18%.
REFERENCES:
patent: 2746905 (1956-05-01), Baum
patent: 3122483 (1964-02-01), Rosenthal
patent: 3689636 (1972-09-01), Svajda
patent: 3863006 (1975-01-01), Hodosh
Outhwaite William C.
Pashley David H.
Drezin Norman A.
Roberts, Jr. John S.
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