Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing
Patent
1993-06-04
1994-10-04
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Fluorine or fluorine compound containing
424 49, 424 57, A61K 716, A61K 718
Patent
active
053524390
ABSTRACT:
An oral composition, such as a toothpaste, includes an anti-tartar proportion of a polyphosphate anti-tartar agent (preferably with synthetic anionic polymeric polycarboxylate or equivalent, and fluoride) and a desensitizing proportion of a tooth pain inhibiting potassium salt which passes through exposed dentin tubules to tooth nerves or neurons, which salt can be potassium nitrate, potassium citrate or potassium oxalate, so that it helps to prevent tartar from forming on the teeth and also lessens any pain experienced by persons contacting their sensitive teeth with the oral composition. Preferably the oral composition is a desensitizing anti-tartar toothpaste or gel which, when the teeth are brushed with it, aids in removal of at least some tartar and prevents its reappearance, and at the same time diminishes any tooth pain that the brusher would otherwise experience due to such brushing. In preferred toothpastes the anti-tartar agent and the desensitizing agent are both potassium compounds and other components of the toothpaste, such as the detergent or surfactant, thickener, water soluble fluoride, anionic polymeric polycarboxylate, sweetener and any anti-calculus agent present, when they may be present as salts, will also be potassium salts.
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Schiff et al "Efficacy of a Dentifrice Containing 5% Potassium Nitrate, 1.3% Soluble Pyrophosphate 1.5% PVM/MA Copolymer, and 0.243% Sodium Fluoride in a Silica Base on Dentinal Hypersensitivity-A Twelve Week Clinical Study" (Exhibit B)(Mar. 21, 1994).
Carter Willie J.
Frankel Matthew J.
Gaffar Abdul
Norfleet James
Colgate - Palmolive Company
Rose Shep K.
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