Descendants of bacteria devoid of N terminal formylation...

Details Descendants of bacteria devoid of N terminal formylation... Descendants of bacteria devoid of N terminal formylation...

2005-11-08

2005-11-08

Ketter, James (Department: 1636)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

C435S252800, C435S069100, C430S350000

Reexamination Certificate

active

06962807

ABSTRACT:
The present invention relates to producing non-formylated proteins and/or peptides in bacterial cells lacking deformylase and/or transformylase.

REFERENCES:
patent: WO 00/34433 (2000-06-01), None
Mazel et al. Genetic characterization of polypeptide deformylase a distinctive enzyme of eubacterial translation. EMBO Journa vol. 13 No. 4 1994 pp. 914-923.
Marolewski et al. Cloning anc characterization of a new pruine biosynthetic enzyme Biochemistry vol. 33 No. 9 pp. 2531-2537 1994.
M. Vulic, et al., Proceedings of the National Academy of Sciences of the United States of America, vol. 96, No. 13, pp. 7348-7351, XP-002220212, “Mutation, Recombination, and Incipient Speciation of Bacteria in the Laboratory”, Jun. 22, 1999.
D. Mazel, et al., EMBO Journal, vol. 13, No. 4, pp. 914-923, XP-002043973, “Genetic Characterization of Polypeptide Deformylase a Distinctive Enzyme of Eubacterial Translation”, Feb. 15, 1994.

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