Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1997-05-14
1998-09-15
Davenport, Avis M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 13, A61K 3800, A61K 3802, C07K 500, C07K 700
Patent
active
058078274
ABSTRACT:
Novel peptides of the invention are dynorphin analogues and have similar activity to endogenous dynorphin, but are des-Tyr or des-Tyr-Gly with respect to endogenous dynorphin and have at least seven amino acid residues. The novel peptides have therapeutic uses, such as administration to a host tolerant to a narcotic analgesic in order to potentiate activity of the narcotic analgesic and/or to block withdrawal symptoms.
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Lee Nancy M.
Loh Horace H.
Takemori Akira E.
Davenport Avis M.
Des-Tyr Dynorphin Partnership
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