Des-Arg.sup.9 -BK antagonists

Details Des-Arg.sup.9 -BK antagonists Des-Arg.sup.9 -BK antagonists

1995-09-08

1998-11-10

Davenport, Avis M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530314, 530327, 530328, A61K 3800, A61K 3802, C07K 500, C07K 700

Patent

active

058344314

ABSTRACT:
The present invention provides des-Arg.sup.9 bradykinin analogs which are selective B1 receptor antagonists.

REFERENCES:
Angiogenic Effect of Bradykinin and Interleukin-1 in Rats," Br. J. Pharmacol., 109, 14-17 (1993).
Marceau, F., et al., "Kinin Receptors of the B1 Type and Their Antagonists," In: Bradykinin Antagonists--Basic and Clinical Research, Burch, R.M., (ed.), Marcel Dekker, Inc., New York, pp. 33-49 (1991).

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