Des-19-leucine, 20-glutamine, 21-threonine-calcitonin

Details Des-19-leucine, 20-glutamine, 21-threonine-calcitonin Des-19-leucine, 20-glutamine, 21-threonine-calcitonin

1987-04-21

1988-08-16

Phillips, Delbert R.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Calcitonin; related peptides

C07K 736

Patent

active

047645903

ABSTRACT:
New peptides are disclosed which have biological activity of the same type as known calcitonins and which do not have a leucine in position 19, a glutamine in position 20, or a threonine in position 21. All three amino acids are omitted. Also resin peptides are disclosed which may be converted to peptides having such biological activity; and processes for producing said resin peptides and said calcitonin peptides.

REFERENCES:
patent: 4632978 (1986-12-01), Seyler et al.
patent: 4639511 (1987-01-01), Orlowski et al.

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