Chemistry: molecular biology and microbiology – Differentiated tissue or organ other than blood – per se – or...
Reexamination Certificate
2004-04-29
2008-12-23
Crouch, Deborah (Department: 1632)
Chemistry: molecular biology and microbiology
Differentiated tissue or organ other than blood, per se, or...
C435S325000, C623S015110
Reexamination Certificate
active
07468242
ABSTRACT:
Embodiments of the present invention provide Dermal Micro Organs (DMOs), methods and apparatuses for producing the same. Some embodiments of the invention provide a DMO including a plurality of dermal components, which substantially retain the micro-architecture and three dimensional structure of the dermal tissue from which they are derived, having dimensions selected so as to allow passive diffusion of adequate nutrients and gases to cells of the DMO and diffusion of cellular waste out of the cells so as to minimize cellular toxicity and concomitant death due to insufficient nutrition and accumulation of waste in the DMO. Some embodiments of the invention provide methods and apparatuses for harvesting the DMO. An apparatus for harvesting the DMO may include, according to some exemplary embodiments, a support configuration to support a skin-related tissue structure from which the DMO is to be harvested, and a cutting tool able to separate the DMO from the skin-related tissue structure. Other embodiments are described and claimed.
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Almon Einat
Bellomo Stephen F.
Bukhman Mordechay
Lippin Itzhak
Pearlman Andrew L.
Cohen Mark S.
Crouch Deborah
Medgenics, Inc.
Noble Marcia S
Pearl Cohen Zedek Latzer LLP
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