Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2007-05-22
2007-05-22
Pak, Michael (Department: 1646)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Reexamination Certificate
active
10239956
ABSTRACT:
The present invention featuresDermacentor variabilisGABA-gated chloride channel polypeptides and nucleic acids, and uses of such polypeptides and nucleic acids.D. variabilisis a widely distributed tick associated with different diseases. A preferred use of the present invention is to obtain compounds for preventing or treating a tick infestation.
REFERENCES:
patent: 5487976 (1996-01-01), Soderlund et al.
patent: 5527703 (1996-06-01), Cully et al.
patent: 5661035 (1997-08-01), Tsien et al.
patent: 5693492 (1997-12-01), Cully et al.
patent: 5767261 (1998-06-01), Wingate et al.
patent: 5852188 (1998-12-01), Cook
patent: 5854002 (1998-12-01), Tomalski et al.
patent: 5859221 (1999-01-01), Cook et al.
patent: 6008046 (1999-12-01), Ffrench-Constant et al.
patent: WO 93/07161 (1993-04-01), None
patent: WO 98/02582 (1998-01-01), None
patent: WO 98/49185 (1998-11-01), None
Henderson, J. et al. “PCR-Based Homology Probing Reveals a Family of GABA Receptor-Like Genes inDrosophila melanogaster”, Insect Biochemistry and Molecular Biology, 1994, vol. 24, pp. 363-371.
Accession No. M69057, Inv. Apr. 26, 1993.
Accession No. O17145, Created Jan. 1, 1998.
Accession No. O18469, Created Jan. 1, 1998.
Chen, R. et al. “Cloning and functional expression of aDrosophila γ-aminobutyricacid receptor”, Proc. Natl. Acad. Sci. USA, 1994, vol. 91, pp. 6069-6073.
ffrench-Constant, R. et al. “Drosophilaγ-Aminobutyric Acid Receptor GeneRdlShows Extensive Alternative Splicing”, Journal of Neurochemistry, 1993, vol. 60, pp. 2323-2326.
Bass, B. “RNA editing and hypermutation by adenosine deamination”, Trends in Biochemical Sciences, 1997, vol. 22, pp. 157-162.
Buckingham, S. et al. “Actions of agonists and convulsant antagonists on aDrosophila melanogasterGABA receptor (Rdl) homo-oligomer expressed inXenopusoocytes”, Neuroscience Letters, 1994, vol. 181, pp. 137-140.
Cupp, E. “Biology of Ticks”, Veterinary Clinics of North America: Small Animal Practice, 1991, vol. 21, pp. 1-26.
Ffrench-Constant, R. et al. “A point mutation in aDrosophilaGABA receptor confers insecticide resistance”, Nature, 1993, vol. 363, pp. 449-451.
Ffrench-Constant, R. et al. “Molecular cloning and transformation of cyclodiene resistance inDrosophila: An invertebrate γ-aminobutyric acid subtype A receptor locus”, Proc. Natl. Acad. Sci. USA, 1991, vol. 88, pp. 7209-7213.
Gonzalez, J. et al. “Improved indicators of cell membrane potential that use fluorescence resonance energy transfer”, Chemistry & Biology, 1997, vol. 4, pp. 269-277.
Hanrahan, C. et al. “RNA Editing ofDrosophilaSodium Channel Gene”, Annals NY Academy of Sciences, 1999, vol. 868, pp. 51-66.
Hosie, A. et al. “Actions of the insecticide fipronil, on dieldrin-sensitive and—resistant GABA receptors ofDrosophila melanogaster”, British Journal of Pharmacology, 1995, vol. 115, pp. 909-912.
Millar, N. et al. “Stable expression of a functional homo-oligomericDrosophilaGABA recptor in aDrosophilacell line”, Proc. R. Soc. Lond. B, 1994, vol. 258, pp. 307-314.
Olsen, R. et al. “Molecular biology of GABAAreceptors”, FASEB J., 1990, vol. 4, pp. 1469-1480.
Rauh, J. et al. “Pharmacological and biochemical properties of insect GABA receptors”, Trends in Pharmacological Sciences, 1990, vol. 11, pp. 325-329.
Smith, A. et al. “Benzodiazepine modulation of recombinant α1β3γ2 GABAAreceptor function efficacy determination using the Cytosensor microphysiometer”, European Journal of Pharmacology, 1998, vol. 359, pp. 261-269.
Cully Doris F.
Ludmerer Steve W.
Zheng Yingcong
Heber Sheldon O.
Merck & Co. Inc
Pak Michael
Struse Heidi M.
Tribble Jack
LandOfFree
Dermacentor variabilis GABA-gated chloride channels does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Dermacentor variabilis GABA-gated chloride channels, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dermacentor variabilis GABA-gated chloride channels will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3759301