Derived nisin producing microorganisms, method of production and

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of...

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4351723, 435253, 435320, 435885, 426531, 426532, 422 40, C12N 100, C12N 1500, C12N 120, C12R 146, B29C 4900, B01J 1118

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047405937

ABSTRACT:
Derived microorganisms containing foreign DNA encoding for nisin production and a method for producing the derived microorganisms by transferring DNA to a recipient microorganism are described. The recipient microorganisms are preferably bacteria lacking in the ability to produce nisin. Nisin inhibits the growth of spoilage bacteria and is used in various materials for preservation, including foods and particularly at refrigeration temperatures. Nisin is also used in animals for improving the health of the animal. The foreign DNA is obtained from a donor microorganism and encodes for nisin production when transferred to the recipient microorganism.

REFERENCES:
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Clewell, "Plasmids, Drug Resistance, and Gene Transfer in the Genus Streptococcus", Microbiol. Rev. 45:409 (1981).
McKay et al., "Conjugal Transfer of Genetic Information in Group N Streptococci", Appl. Env. Microbiol. 40:84 (1980).
Lipinske et al., "Selection of Phage-Resistant Nisin-Producing Streptococci", Chem. Abstr. 87:165968f (1977) of Rocz. Inst. Przem. Mlecz. 18(3), 5 (1976).
Reddy et al., "The Influence of Lactic Cultures on Ground Beef Quality", J. Food Sci. 35:787 (1970).
Reddy et al., "Influence of Lactic Cultures on the Biochemical, Bacterial, and Organoleptic Changes in Beef", J. Food Sci. 40:314 (1975).

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