Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – From reactant having at least one -n=c=x group as well as...
Reexamination Certificate
2005-05-31
2005-05-31
Gorr, Rachel (Department: 1711)
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
From reactant having at least one -n=c=x group as well as...
C525S452000, C525S453000, C525S454000, C521S053000
Reexamination Certificate
active
06900282
ABSTRACT:
A process for preparing the polyurethane derivative, the process including: providing a polyurethane having a urethane amino moiety, providing a multifunctional linker reagent of a formula: LG-RL-(FG)n, wherein n is an integer from 1 to 3, FG is a functional group, which is a halogen, a carboxyl group, a sulfonate ester, or an epoxy group, LG is a leaving group, which is a halogen, a carboxyl group, a sulfonate ester, or an epoxy group, and RLis an (n+1)-valent organic radical having at least one carbon atom; providing a protected thiol-containing reagent of a formula R—C(O)SH, or a salt thereof, wherein R is a C1to C6alkyl group; reacting the multifunctional linker reagent with the urethane amino moiety to form a polyurethane substituted with at least one substituent group of a formula: —RL-(FG)n; reacting the polyurethane with a protected thiol-containing reagent to form the polyurethane derivative.
REFERENCES:
patent: 4521564 (1985-06-01), Solomon et al.
patent: 4642242 (1987-02-01), Solomon et al.
patent: 4746654 (1988-05-01), Breliere et al.
patent: 5073575 (1991-12-01), Blanch et al.
patent: 5134035 (1992-07-01), Kumar et al.
patent: 5159050 (1992-10-01), Onwumere
patent: 5855618 (1999-01-01), Patnaik et al.
patent: 6320011 (2001-11-01), Levy et al.
patent: WO 95 20008 (1995-07-01), None
Phaneuf, M.D. et al., “Covalent Linkage of Recombinant Hirudin to a Novel Ionic Poly (Carbonate) Urethane Polymer with Protein Binding Sites: Determination of Surface Antithrombin Activity”, Artif. Organs 1998; 22:657-65.
Huang, L.L.H. et al., “Comparison of Epoxides on Grafting Collagen to Polyurethane and Their Effects on Cellular Growth”, J. Biomed. Mater. Res. 1998; 39:630-6.
Lincoff et al., J.Am. Coll. Cardiol., 29, 808. 16 (1997).
Adibi et al., 1979, Polymer 20:483-487.
Mikroyannidis, 1984, J. Polymer Sci., Polymer Chem. Ed. 22:891-903.
Baumgartner et al., 1996, Asaio J. 42:M476-M479.
Grasel et al., 1987, J. Biomed. Mat. Res. 21:815-842.
Sivriev H et al., “Phosphorus-Containing Polyurethanes, Prepared by N-Modification”, European Polymer Journal, 1990, pp. 73-76, vol. 26, No. 1, Pergamon Press Ltd., Oxford, GB.
Joshi, R. et al., “Calcification of Polyurethanes Implanted Subdermally in Rats is Enhanced by Calciphylaxis”, Journal of Biomedical Materials Research, vol. 31, pp. 201-207, John Wiley & Sons, 1996.
Alferiev Ivan
Fishbein Ilia
Levy Robert J.
Caesar Rivise Bernstein Cohen & Pokotilow Ltd.
Gorr Rachel
The Children's Hospital of Philadelphia
LandOfFree
Derivatized polyurethane compositions which exhibit enhanced... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Derivatized polyurethane compositions which exhibit enhanced..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Derivatized polyurethane compositions which exhibit enhanced... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3443731