Derivatized calcitonins

Details Derivatized calcitonins Derivatized calcitonins

1993-12-30

1998-01-20

Weimar, Elizabeth C.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Calcitonin; related peptides

514 6, 514 12, 514808, A61K 3823, C07K 14585

Patent

active

057102449

ABSTRACT:
Derivatized calcitonin molecules, pharmaceutical compositions comprising derivatized calcitonins, and methods of reducing serum calcium in a patient using the derivatized calcitonins are disclosed. The molecules are characterized by a derivatized amino terminus formed by combining a calcitonin with a cyclic, polycyclic or heterocyclic moiety. Multimeric forms of the molecules are also disclosed.

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