Chemistry: analytical and immunological testing – Including sample preparation
Patent
1987-09-22
1991-02-05
Warden, Robert J.
Chemistry: analytical and immunological testing
Including sample preparation
436128, 436129, 436161, 560130, 560204, 560236, 560265, C07C 6700, C07C 6710, G01N 3002, G01N 3300
Patent
active
049904582
ABSTRACT:
A process for forming derivatives of organic compounds as a step during their analysis. A macroreticular resin is used as both an adsorbent for the analyte and the derivatizing reagent and also as a catalyst for the derivatization reaction. Subsequent serial elution of the absorbed compounds leads to simple separation of the derivatized analyte from the starting materials. Further, the resin impregnated with derivatizing reagent can be used to combine the extraction and derivatization of the analyte. As macroreticular resins are relatively inexpensive, they result in reduced costs compared with conventional catalysts, and their ease of separation from liquid systems makes them easy to use and makes it possible to automate the procedure.
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McMaster University
Trautman Kimberly A.
Warden Robert J.
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