Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1995-06-06
1997-04-29
Wilson, James O.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 2, 514 25, 514 53, 514 54, 514 61, 514563, 435 71, A01N 3700, A01N 3900, A61K 3100, A61K 3156
Patent
active
056249098
ABSTRACT:
Triterpenoid acid derivatives have been found to have structures similar to natural ligands to the extent that these derivatives bind to natural selectin receptors including endothelial leukocyte adhesion molecule-1 (ELAM-1) and leukocyte/endothelial cell adhesion molecule-1 (LECAM-1). The molecules can be administered to the patients by themselves or in pharmaceutical formulations in order to alleviate inflammation and/or treat other abnormalities associated with the excessive binding of leukocytes to endothelial receptors.
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Anderson Mark B.
Musser John H.
Naleway John J.
Rao Narasinga
Glycomed Incorporated
Wilson James O.
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