Derivatives of thieno-triazolo-diazepine and therapeutic composi

Details Derivatives of thieno-triazolo-diazepine and therapeutic composi Derivatives of thieno-triazolo-diazepine and therapeutic composi

1992-02-18

1996-02-20

Datlow, Philip I.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

540555, A61K 3155, C07D49522

Patent

active

054929067

ABSTRACT:
The invention relates to thieno-triazolo-diazepine derivatives of the formula: ##STR1## wherein Y stands for oxygen or sulphur and R stands for various substituents, to a preparation process of said compounds and to therapeutic compositions containing the same. The compounds are particularly interesting as anti-asthmatic, anti-allergic and gastro-intestinal protectors.

REFERENCES:
Weber, CA 109:129067a (1988).
Burgers Medicinal Chemistry and Drug Discovery, 5th ed. (1995), Wolft, editor, pp. 783-788.
Silverman, The Organic Chemistry of Drug Design and Drug Action, 1992, Academic Press, pp. 19-23.
Burger, Medicinal Chemistry, 2nd ed (1960), Interscience Publishers, New York, pp. 72-78.
Noller, Chemistry of Organic Compounds, 2nd ed. (1957), p. 272.
Conant et al, The Chemistry of Organic Compounds, 5th ed. (1959), p. 333.

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