Derivatives of thiadiazolo[3,4-d]pyrimidine

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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424251, C07D23970

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active

041277210

ABSTRACT:
9-(Dihalobenzyl)adenines are prepared uncontaminated with other positional isomers in a series of mild transformations starting from 4,5,6-triaminopyrimidine and proceeding via 7-(N-formyl-N-dihalobenzyl)-amino[1,2,5]thiadiazolo[3,4-d]pyrimidine. The resulting compounds have anticoccidial activity and are useful in controlling cecal and/or intestinal coccidiosis when administered in minor quantities to animals, in particular to poultry usually in admixture with animal sustenance.

REFERENCES:
patent: 3225048 (1965-12-01), Menzl
patent: 3819631 (1974-06-01), Broughton et al.
patent: 3933822 (1976-01-01), Broughton et al.
patent: 3956326 (1976-05-01), Niess et al.
patent: 3959280 (1976-05-01), Furukawa et al.

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