Derivatives of the oxime of 1,2,5,6-tetrahydropyridine 3-carboxa

Details Derivatives of the oxime of 1,2,5,6-tetrahydropyridine 3-carboxa Derivatives of the oxime of 1,2,5,6-tetrahydropyridine 3-carboxa

1992-04-01

1993-07-27

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

546326, C07D21170, A61K 3144

Patent

active

052311074

ABSTRACT:
Compounds useful in the treatment of patients suffering from senile dementia, Alzheimer's disease or memory defects, of the formula ##STR1## in which R' represents hydrogen, a linear, branched or cyclic alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, and R represents a linear, branched or cyclic alkyl, alkenyl, or alkynyl, containing up to 18 carbon atoms, possibly substituted, aryl containing up to 14 carbon atoms, possibly substituted, aralkyl containing up to 18 carbon atoms, possibly substituted, as well as their addition salts with organic or mineral acids, and to compounds of formula (I) in which R represents phenyl substituted in the 4 position by Br, F, CH.sub.3, NO.sub.2 or C(CH.sub.3).sub.2 C(CH.sub.3).sub.3 and R' represents CH.sub.3.

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