Derivatives of tetrapeptides as CCK agonists

Details Derivatives of tetrapeptides as CCK agonists Derivatives of tetrapeptides as CCK agonists

1991-06-17

1993-12-14

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 17, 514 19, 530330, 530331, A61K 3702, C07K 508, C07K 510

Patent

active

052703029

ABSTRACT:
Selective and potent Type-A CCK receptor agonists of formula (I):

REFERENCES:
patent: 2932635 (1960-04-01), Amiard et al.
patent: 4687760 (1987-08-01), Martinez et al.
patent: 4808701 (1989-02-01), Darho et al.
patent: 4818748 (1989-04-01), Bender et al.
Vanderhaeger et al., Neuronal Cholecystokinin, 1985 pp. 461-462, 593, 599.
Miyamoto et al.,-Chem. Pharm. Bull., 1986, 34(2) pp. 694-700.
Stewart et al., (Solid Phase Peptide Synthesis, 2nd Ed, 1984, Pierce Chemical Company, Rockford, Ill., pp. 27 and 28.
Martinez, et al., J. Med., Chem. 1985, 28:1874.
Yabe et al., Chem. Pharm. Bull., 1977, 25:2731.
Kovacs et al., "Cholesystokinin Analogs Containing Non-Coded Amino Acids", Pept Synthesis, Structure and Function, Proc. 9th Am. Pept. Symp., 1985, pp. 583-586.

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