Derivatives of tetrahydro-1H-1,3-diazepine and hexahydro-1,3-dia

Details Derivatives of tetrahydro-1H-1,3-diazepine and hexahydro-1,3-dia Derivatives of tetrahydro-1H-1,3-diazepine and hexahydro-1,3-dia

1975-05-29

1976-12-07

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424244, C07D24304, C07D24502

Patent

active

039962075

ABSTRACT:
The disclosure relates to derivatives of tetrahydro-1H-1,3-diazepine and hexahydro-1,3-diazocine of the general formula ##STR1## or pharmaceutically acceptable acid addition salts thereof wherein n represents 2 or 3, R.sup.3 and R.sup.4 which may be the same or different each represent hydrogen or lower alkyl, Ph represents phenyl, halophenyl, lower alkyl phenyl, di(lower alkyl) phenyl or lower alkoxy phenyl, R is hydroxyl, lower alkoxy or halogen, R.sup.1 is phenyl, halophenyl, lower alkyl phenyl, di(lower-alkyl phenyl, lower alkoxyphenyl or naphthyl and R.sup.6 is hydrogen or lower alkyl. The compounds have hypoglycemic activity.

REFERENCES:
patent: 3657229 (1972-04-01), Bailey

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