Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-03-26
1995-10-24
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514322, 544271, 544272, 544370, 546199, C07D40112, C07D24702, C07D47308
Patent
active
054610591
ABSTRACT:
##STR1## The present invention concerns (4-substituted phenyl)4-oxy 1-aminobutane of the general formula (I) in which X is a nitrogen atom or >CH--CH, and R is a cyclic substituent chosen from the group comprising a) a xanthic substituent, b) a benzimidazolic substituent, as well as salts and optic isomers of the compounds of formula (I). The invention also concerns processes for obtaining the compounds of formula (I) and pharmaceutical compositions containing, as antihistamine ingredient, at least one compound of formula (I) or one of its salts with a mineral or organic acid.
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patent: 4219559 (1980-08-01), Janssens
patent: 4430343 (1984-02-01), Iemura
patent: 4908372 (1990-03-01), Carr
patent: 5278165 (1994-01-01), Janssens
Janssens, J. Med. Chem. 28, 1925 (1985).
Bonnet Paule
Delansorne Remi
Faure Maurice
Languetin Michel
Zunino Serge
Berch Mark L.
Laboratoire Theramex S.A.
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