Derivatives of succinic and glutaric acids and analogs...

Details Derivatives of succinic and glutaric acids and analogs... Derivatives of succinic and glutaric acids and analogs...

2008-04-29

2008-04-29

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S080000, C514S419000, C514S559000, C548S469000, C548S503000, C548S506000, C548S494000, C562S405000

Reexamination Certificate

active

11441764

ABSTRACT:
The present invention relates to derivatives of succinic and glutaric acids and analogues thereof, having the following general formula:useful as inhibitors of PHEX. These derivatives are useful for promoting generation of bone mass and treating or preventing diseases or conditions associated with a phosphate metabolism defect. Methods for preparation and intermediates are also disclosed.

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