Derivatives of substituted n-alkyl imidazoles

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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548341, A61K 31415, C07D23360

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active

040597059

ABSTRACT:
Compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 are each independently alkyl, cyclohexyl substituted with from one to three lower alkyl groups, or a group of the formula ##STR2## WHEREIN M IS AN INTEGER OF FROM 0 TO 3 AND P IS AN INTEGER OF FROM 1 TO 3; X is sulfur or oxygen; n is an integer of from 1 to 8; and the antimicrobial acid addition salts thereof are useful as antifungal, antibacterial and antiprotozoal agents.

REFERENCES:
patent: 3531494 (1970-09-01), Adolphi et al.
patent: 3551444 (1970-12-01), Shen et al.
DU Vigneaud et al., J. Amer. Chem. Soc., 1948, vol. 70, pp. 1620-1624.
Skvortsova et al., Chem. Abst., 1970, vol. 72, No. 121437t.

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