Derivatives of ryanodine and dehydroryanodine

Details Derivatives of ryanodine and dehydroryanodine Derivatives of ryanodine and dehydroryanodine

1995-05-17

1996-04-23

McKane, Joseph K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Azides

C07C 2502

Patent

active

055105009

ABSTRACT:
Novel O.sub.10eq -derivatives of ryanodine and dehydroryanodine characterized as binding strongly to ryanodine receptor, useful in affecting Ca.sup.++ efflux in tissue and also in isolating ryanodine receptor from sarcoplasmic reticulum. Also described are novel radio-iodinated alanine derivatives useful to radio label ryanodine and dehydroryanodine derivatives.

REFERENCES:
CA 120:290037k O.sub.10 -O.sub.eq -N-. . . site. Bidasse et al., p. 1025, 1994.

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