Derivatives of ryanodine and dehydroryanodine

Details Derivatives of ryanodine and dehydroryanodine Derivatives of ryanodine and dehydroryanodine

1993-03-02

1995-07-11

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548405, 548525, 548532, 548535, C07D20730, C07D23502

Patent

active

054322880

ABSTRACT:
Novel O.sub.10eq -derivatives of ryanodine and dehydroryanodine characterized as binding strongly to ryanodine receptor, useful in affecting Ca.sup.++ efflux in tissue and also in isolating ryanodine receptor from sarcoplasmic reticulum. Also described are novel radio-iodinated alanine derivatives useful to radio label ryanodine and dehydroryanodine derivatives.

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