Derivatives of pyridine-3-acetic acid, process for their prepara

Details Derivatives of pyridine-3-acetic acid, process for their prepara Derivatives of pyridine-3-acetic acid, process for their prepara

1974-10-15

1977-03-08

Drezin, Norman A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602955R, 2602955T, A61K 3144, C07D21316

Patent

active

040113280

ABSTRACT:
The present invention provides compounds of formula: ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen, halog alkyl having from 1 to 6 carbon atoms, alcoxy having from 1 to 6 carbon atoms and alkylthio having from 1 to 6 carbon atoms,
A taken separately is hydrogen and B is a radical with the formula ##STR2## , R.sub.3 being selected from the group consisting of hydrogen, halogen and alcoxy having from 1 to 6 carbon atoms, and A and B taken together form a radical --O--CH.sub.2 --, and the esters, N oxides and pharmacologically acceptable salts of the acids of Formula I.
These compounds have analgesic and antiinflammatory properties.

REFERENCES:
patent: 3699227 (1972-10-01), Doyle et al.
patent: 3715358 (1973-02-01), Witzel et al.
Doyle et al., Chemical Abstracts, 71:38813w (1969).
Doyle et al., Chemical Abstracts, 72:12592u (1970).
Mitchell, Chemical Abstracts, 76:140540v (1972).

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