Derivatives of pyrazole-5-acetic acid

Details Derivatives of pyrazole-5-acetic acid Derivatives of pyrazole-5-acetic acid

1975-06-23

1976-10-05

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424273, 2602475E, C07D23114

Patent

active

039844315

ABSTRACT:
Compounds having anti-inflammatory and antipyretic action have the general formula ##SPC1##
In which each of R.sub.1 and R.sub.2 is a phenyl group which may be substituted by a halogen atom, an alkyl or alkoxy group having 1 to 4 carbon atoms or a trifluoromethyl group, R.sub.3 is a straight or branched chain saturated or unsaturated aliphatic hydrocarbon group or a cycloaliphatic hydrocarbon group having 3 to 7 carbon atoms, or a benzyl or phenyl group which benzyl or phenyl groups may be substituted in the benzene ring by a halogen atom, an alkyl or alkoxy group having 1 to 4 carbon atoms or a trifluoromethyl group or by any two of these substituents, R.sub.4 is a hydrogen atom or an alkyl group having 1 to 4 carbon atoms and A is a group having one of the formulae --COOH, --COOR.sub.5 and --CONR.sub.6 R.sub.7 in which R.sub.5 is an alkyl group having 1 to 4 carbon atoms or a benzyl group and each of R.sub.6 and R.sub.7 is a hydrogen atom or an alkyl group having 1 to 4 carbon atoms or R.sub.6 and R.sub.7 taken together with the nitrogen atom to which they are attached represents a pyrrolidino, a piperidino or a morpholino group.

REFERENCES:
patent: 3704241 (1972-11-01), Noguchi et al.

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