Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-04-03
1996-10-15
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514261, A61K 3152, C07D47318, C07D47332, C07D47316
Patent
active
055654614
ABSTRACT:
The present invention is directed to a method of treating an HIV infection in a host in need of such treatment which comprises administering an effective anti-HIV amount of a compound having the formula ##STR1## wherein: R.sup.1 is hydrogen, hydroxyl;
REFERENCES:
patent: 4199574 (1980-04-01), Schaefler
patent: 4565868 (1986-01-01), Verheyden et al.
patent: 4590269 (1986-05-01), Prisbe et al.
patent: 4714701 (1987-12-01), Beauchamp
Lundgren. J. Acquired Immune Def. Syndrome 4, 489-498 (1991).
Wyand, AIDS Res & Hum ret 8, 349(1992).
Martin et al Antiviral Res 1990, 1(Suppl) p. 114.
Wahren, Antimicrobial Agents & Chemotherapy 32(8), pp. 1137-1142 (1988).
Connolly, Antimicro. Agents & Chemo. 36, 245 (1992).
De Clercq, AIDS Res & Hum. Ret. 8, 119 (1992).
Dr. Sandstrom Letter of Jun. 19, 1990.
Mansuri et al, Chem. Tech, Sep. 1992, p. 564.
Sgari, J Med Chem 35, 3792 (1992).
Merck Standby Statement of Sep. 14, 1993.
Antiviral Agents Bulletin 6, p. 162 (Jun. 1993).
Antiviral Agents Bulletin 6, p. 260 (Sep. 1993).
Antiviral Agents Bulletin 6, 228, Aug. 1993.
Flexner, Antimicro Agents & Chemotherap 35, 2544 (1991).
Staal, AIDS Res. & Hum. Retroviruses 9, 299 (1993).
Saunders, Drug Design & Discovery, 8, 255 (1992).
Tsai. J. Infec. Diseases 169, 260 (1994).
Grand, J. Med. Primatol. 23, 256-257 (1994).
Cundy, Anti Microb Agents & Chemo. 38, 365 (1994).
Bree, J. Med. Primatol. 23, 260-261 (1994).
Tsai, J. AIDS 6, 1086 (1993).
Wakrim et al, J. Med. Primatology 23(4), pp. 247-248.
Hu et al. Med. Primatology, 23, (4), p. 239 (1994).
Bartz, J. Med. Primatology 23, 255 (1994).
Larsson et al., Antimicrobial Agents and Chemotherapy, vol. 30, No. 4, pp. 598-605 (1986).
Abele et al, Antimicrobial Agents and Chemotherapy, vol. 31, No. 1, pp. 76-80 (1987).
Bottiger, Disa, Evaluation of HIV Inhibitors in Macaques Infected with SIV and HIV-2, Dept. of Microbiology and Tumorbiology, Karolinska Institute, Stockholm, Sweden (1994).
Lake-Bakaar, Desmond et al., Antimicrobial Agents and Chemotherapy, vol. 33, No. 1, pp. 110-112 (1989).
Kuller, J. Med. Primalol. 23, 262 (1994).
Gallimore, J. Med Primatol. 23, 287 (1994).
Putkonen, J. Med. Primatol. 23, 269 (1994).
Titti, J. Med. Primatol. 23 258 (1994).
Flexner, J Infect. Diseases 170, 1394 (1994).
Datema Roelf
Johansson Karl N. G.
Lindborg Bj orn G.
Oberg Bo F.
Berch Mark L.
Medivir AB
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