Derivatives of porphyrin useful in photodynamic therapy

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D48722, A61K 3140

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050649523

ABSTRACT:
Compounds which are long wavelength-absorbing derivatives of porphyrinone nuclei are described which are useful in photodynamic therapy and related technologies. These compounds contain the porphyrin nucleus beta-substituted with alkyl and/or omega-carboxyalkyl substituents wherein the ring system contains at least one exocyclic double bond in which the exocyclic participant is selected from the group consisting of .dbd.S, .dbd.CR'.sub.2, and NR".

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