Derivatives of polyene macrolide antibiotics containing an amino

Details Derivatives of polyene macrolide antibiotics containing an amino Derivatives of polyene macrolide antibiotics containing an amino

1980-03-07

1981-06-09

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

424180, 424181, 2601125R, 536 17R, A61K 3700, A61K 3170, C07C10352, C07H 1916

Patent

active

042725259

ABSTRACT:
This invention relates to derivatives of polyene macrolide antibiotics containing an amino sugar moiety, the process for their preparation and pharmaceutical compositions containing them useful in the treatment of fungal infections.

REFERENCES:
patent: 4035567 (1977-07-01), Sipos
Chemical Abstract, vol. 77, 1972, p. 36, Abst. No. 97013g, Mechlinski et al., "Polyene macrolide derivatives, I. N.-acylation and esterification reaction with amphotericin B".
Chemical Abstracts, vol. 80, 1974, p. 471, Abst. No. 121291f, Ferrari et al., "Alkyl esters of polyene antibiotics".

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