Derivatives of penicillanic acid and compositions containing the

Details Derivatives of penicillanic acid and compositions containing the Derivatives of penicillanic acid and compositions containing the

1975-10-24

1976-07-13

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424271, C07D49948

Patent

active

039693422

ABSTRACT:
Derivatives of penicillanic acid of formula: ##SPC1##
In which R represents hydrogen or a radical of formula: ##EQU1## which is easily removable enzymatically, and in which R.sub.1 is hydrogen or straight or branched chain C.sub.1-4 alkyl, phenyl, or phenyl C.sub.1-2 alkyl and R.sub.2 is straight or branched chain C.sub.1-4 alkyl or alkoxy, cyclohexyl, phenyl or phenyl C.sub.1-2 alkyl, together with their pharmaceutically acceptable non-toxic metal salts or addition salts with nitrogen-containing bases, have particularly valuable anti-bacterial properties, especially against Gram-positive and Gram-negative bacteria.

REFERENCES:
patent: 3577408 (1971-05-01), Alburn et al.
patent: 3734904 (1973-05-01), Wendt et al.
patent: 3821198 (1974-06-01), Lee et al.
patent: 3873524 (1975-03-01), Sellstedt et al.

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