Derivatives of indole-3-carboxamide, preparation method...

Details Derivatives of indole-3-carboxamide, preparation method... Derivatives of indole-3-carboxamide, preparation method...

2007-04-10

2007-04-10

McKane, Joseph K. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S419000, C548S492000, C548S493000, C548S494000, C548S503000

Reexamination Certificate

active

11138843

ABSTRACT:
The invention relates to derivatives of indole-3-carboxamide having general formula (I):wherein: R1represents a C3–C10alkyl, a C5–C10carbocyclic radical that is unsubstituted or substituted one or more times with a methyl group; R2represents a hydrogen atom or a (C1–C4)alkyl group; R3represents a halogen atom or a (C1–C4)alkyl group; R4represents a hydrogen or halogen atom or a (C1–C4)alkyl group; R5represents a (C1–C4)alkyl group or a trifluoromethyl; X represents a sulfur atom, an —NHSO2— group or an —SO2— group; and n is equal to 2 or 3. The invention also relates to a method of preparing the aforementioned derivatives and to the application of same in therapeutics.

REFERENCES:
patent: 4973587 (1990-11-01), Ward et al.
patent: WO 01/58869 (2001-08-01), None
patent: WO 02/42269 (2002-05-01), None

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