Derivatives of epothilone B and D and synthesis thereof

Details Derivatives of epothilone B and D and synthesis thereof Derivatives of epothilone B and D and synthesis thereof

2005-05-31

2005-05-31

Shameem, Golam M M (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S203000

Reexamination Certificate

active

06900331

ABSTRACT:
The present invention provides the following new compounds: (R)-C14-methyl-epothilone B, (S)-C14-methyl-epothilone B, (S)-C14-methyl-epothilone D, and (R)-C14-methyl-epothilone D and methods for synthesizing these compounds.

REFERENCES:
patent: 6262094 (2001-07-01), Hoefle et al.
patent: 6288237 (2001-09-01), Hoefle et al.
patent: 6380227 (2002-04-01), Mutz
patent: 6489314 (2002-12-01), Ashley et al.
patent: 6589968 (2003-07-01), Arslanian et al.
patent: 6613912 (2003-09-01), Hoefle et al.
patent: 6624310 (2003-09-01), Hoefle et al.

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