Derivatives of diphtheria toxin, process for preparing them and

Details Derivatives of diphtheria toxin, process for preparing them and Derivatives of diphtheria toxin, process for preparing them and

1975-10-09

1977-07-05

Shapiro, Lionel M.

Textiles: fiber preparation

424 92, C12D 700, C12K 500

Patent

active

040338193

ABSTRACT:
Process for preparing a derivative of the fragment B of diphtheria toxin, which comprises treating an aqueous solution of the diphtheria toxin with an aliphatic mono- or di-aldehyde having a chain length of 1 to 6 carbon atoms at an aldehyde concentration of 0.0015 M to 0.035 M, at 1.degree. to 20.degree. C, for 5 minutes to 50 hours, reacting the toxin, before or after the treatment with aldehyde, in the presence of a compound splitting off di-sulfide bridges, with a proteolytic enzyme, recovering the derivative of fragment B from the solution obtained in the presence of a denaturing agent by protein-chemical isolation processes and separating it from the denaturing agent.

REFERENCES:
patent: 3888837 (1975-06-01), Tsumita et al.

Affiliated with

Also associated with

Rating

Derivatives of diphtheria toxin, process for preparing them and does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Derivatives of diphtheria toxin, process for preparing them and , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Derivatives of diphtheria toxin, process for preparing them and will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-575602