Derivatives of coenzyme B.sub.12

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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424201, 536 25, A61K 3152, C07H 1918

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active

043649394

ABSTRACT:
Novel monoesters of cobamide derivatives of coenzyme B.sub.12 of the formula: ##STR1## wherein R is acyl of an organic carboxylic acid of 4 to 20 carbon atoms and Co is .alpha.-(5,6-dimethyl-benzimidazolyl)-cobamide which is a mixture of the said monoesters having dibencozide type properties and a process for their preparation.

REFERENCES:
patent: 3095413 (1963-06-01), Sasse et al.
patent: 3151116 (1964-09-01), de Stevens et al.
patent: 3213082 (1965-10-01), Smith et al.
patent: 3573276 (1971-03-01), Wagner

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