Derivatives of clavulanic acid, a process for their preparation

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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542420, 2602453, C07D49804, A61K 3142

Patent

active

044263899

ABSTRACT:
The compounds of the formula (II): ##STR1## pharmaceutically acceptable salts thereof, esters thereof and acid addition salts thereof wherein X is a C.sub.1-6 alkylene group, a C.sub.3-8 cycloalkylene group or a C.sub.3-8 cycloalkyl C.sub.1-4 alkylene group, have been found to be .beta.-lactamase inhibitors and antibacterial agents. Their preparation and use is described.

REFERENCES:
patent: 4228174 (1980-10-01), Ponsford
patent: 4229443 (1980-10-01), Binderup
patent: 4231928 (1980-11-01), Naito
patent: 4237051 (1980-12-01), McCombie
patent: 4244965 (1981-01-01), Howarth
patent: 4246262 (1981-01-01), Vangedal
patent: 4278686 (1981-07-01), Corbett

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