Derivatives of cis, endo-2-azabicyclo[5.3.0]decane-3-carboxylic

Details Derivatives of cis, endo-2-azabicyclo[5.3.0]decane-3-carboxylic Derivatives of cis, endo-2-azabicyclo[5.3.0]decane-3-carboxylic

1983-12-14

1987-12-22

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548452, C07D20902, A61K 3140

Patent

active

047147083

ABSTRACT:
The invention relates to derivatives of cis,endo-2-azabicyclo[5.3.0]decane-3-carboxylic acid of the formula I ##STR1## in which R denotes hydrogen, alkyl, alkenyl or aralkyl, R.sup.1 denotes hydrogen, allyl, vinyl or a side chain of an optionally protected naturally occurring .alpha.-aminoacid, R.sup.2 denotes hydrogen, alkyl, alkenyl or aralkyl, Y denotes hydrogen or hydroxyl, Z denotes hydrogen, or Y and Z together denote oxygen, X denotes alkyl, alkenyl, cycloalkyl, aryl which can be substituted once, twice or three times by alkyl, alkoxy, hydroxyl, halogen, nitro, amino, alkylamino, dialkylamino or methylenedioxy, or denotes indol-3-yl, and their physiologically acceptable salts, a process for their preparation, agents containing them and their use.

REFERENCES:
patent: 3113950 (1963-12-01), Sunagawa et al.

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