Derivatives of choline binding proteins for vaccines

Details Derivatives of choline binding proteins for vaccines Derivatives of choline binding proteins for vaccines

2005-03-08

2005-03-08

Minnifield, N. M. (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

C424S184100, C424S234100, C424S237100, C424S244100, C530S350000, C530S300000, C514S002600, C514S008100

Reexamination Certificate

active

06863893

ABSTRACT:
The present invention provides bacterial immunogenic agents for administration to humans and non-human animals to stimulate an immune response. It particularly relates to the vaccination of mammalian species with pneumococcal derived polypeptides that include an alpha helix but exclude a choline binding region as a mechanism for stimulating production of antibodies that protect the vaccine recipient against infection by pathogenic bacterial species. In another aspect the invention provides antibodies against such proteins and protein complexes that may be used as diagnositics and/or as protective/treatment agents for pathogenic bacterial species.

REFERENCES:
patent: 5997882 (1999-12-01), Briles et al.
patent: 6231870 (2001-05-01), Briles et al.
patent: 6232116 (2001-05-01), Briles et al.
patent: 6245335 (2001-06-01), Masure et al.
patent: 6291654 (2001-09-01), Hostetter et al.
patent: 6500613 (2002-12-01), Briles et al.
patent: 6503511 (2003-01-01), Wizemann et al.
patent: 6573082 (2003-06-01), Choi et al.
patent: 6582706 (2003-06-01), Johnson et al.
patent: 6656472 (2003-12-01), Chong et al.
patent: 6689369 (2004-02-01), Koenig et al.
patent: 6784164 (2004-08-01), Masure et al.
patent: 20020061545 (2002-05-01), Choi et al.
patent: 20030059438 (2003-03-01), Briles et al.
patent: 20030091577 (2003-05-01), Gilbert et al.
patent: 20030096950 (2003-05-01), Tuomanen et al.
patent: 20030138447 (2003-07-01), Wizemann et al.
patent: 20040001836 (2004-01-01), Johnson et al.
patent: 20040005331 (2004-01-01), Johnson et al.
patent: 20040052781 (2004-03-01), Johnson et al.
patent: 20040120966 (2004-06-01), Tuomanen et al.
patent: WO 9741151 (1997-11-01), None
patent: WO 9818930 (1998-05-01), None
patent: WO 9821337 (1998-05-01), None
patent: WO 9951187 (1999-10-01), None
patent: WO 9951266 (1999-10-01), None
Jarva et al, Molecular Immunology, 2003, 40:95-107.*
Briles et al, International Congress Series, 2003, 1257:27-31.*
Briles, Mechanisms of Aging and Development, 2004, 125/2:129:131.*
Brooks-Walter et al, Infection and Immunity, 1999, 67/12:6533-6542.*
Hammerschmidt et al, Mol. Microbiol., 1997, 25/6:1113-1124.

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