Derivatives of chenodeoxycholic acid

Details Derivatives of chenodeoxycholic acid Derivatives of chenodeoxycholic acid

1982-06-28

1984-03-27

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07J 1300

Patent

active

044393660

ABSTRACT:
Novel compounds are described, which are 7-acyl-chenodeoxycholic acid of formula (I) ##STR1## in which R-CO is the residue from a linear, saturated or unsaturated carboxylic acid of 3-18 carbon atoms or the residue from a cycloalkanecarboxylic acid of 3-7 carbon atoms in the cycloalkane ring. The compounds are prepared by selective hydrolysis of the 3,7-diacyl derivatives of chenodeoxycholic acid. The compounds are valuable against biliary calculosis, diskinesia and hypertriglyceridemia.

REFERENCES:
patent: 3833620 (1974-09-01), Saltzman
patent: 3969503 (1976-07-01), Saltzman

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