Derivatives of butyric acid and uses thereof

Details Derivatives of butyric acid and uses thereof Derivatives of butyric acid and uses thereof

2006-04-25

2006-04-25

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S105000, C544S172000

Reexamination Certificate

active

07034020

ABSTRACT:
The present invention provides a series of compounds having structural formulaswherein n1is 1 to 5, n2is 1 to 4 and m is 1 to 3; X is O or NH; Y is CH2, O, S, NH, NR; R is selected from the group consisting a straight-chain aliphatic group, a branched-chain aliphatic group and an alicyclic group; wherein R′ is selected from the group consisting of hydrogen, methyl and ethyl; when Y is O, n1is not 1; and wherein X and R′ are independently optionally substituted at C2, C3 or C4 in compounds of Fomula IV or a pharmaceutically acceptable salt thereof. Also provided is a method of inactivating antigen-specific T cells in a n individual.

REFERENCES:
Oguro, 1995, CAS:122:322532.
Kotelko et al., 1973, CAS: 79:105217.
Kadlubowski, 1979, CAS: 90:197759.

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