Derivatives of bicyclic amino acids, agents containing them and

Details Derivatives of bicyclic amino acids, agents containing them and Derivatives of bicyclic amino acids, agents containing them and

1989-04-03

1990-04-24

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514414, A61K 3140, A61K 31465, C07D40312, C07D20902

Patent

active

049201441

ABSTRACT:
The invention relates to new derivatives of the bicyclic amino acids of the formula I ##STR1## in which n denotes 0, 1 or 2, R denotes hydrogen, alkyl or aralkyl, R.sup.1 denotes hydrogen or alkyl, alkenyl, cycloalkyl, cycloalkenyl, cycloalkylalkyl, optionally substituted aryl or partially hydrogenated aryl, aryl-(C.sub.1 to C.sub.4)-alkyl or aroyl-C.sub.1 -alkyl, both of which can be substituted, a monocyclic or bicyclic heterocyclic radical or a side chain of a naturally occurring amino acid, R.sup.2 denotes hydrogen, alkyl, alkenyl or aralkyl, X denotes alkyl, alkenyl, cycloalkyl or aryl which can be substituted, or 3-indolyl, and to their salts, to a process for their preparation, to agents containing them, and to their use.

REFERENCES:
patent: 4562202 (1985-12-01), Urbach et al.
patent: 4587258 (1986-05-01), Gold et al.

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