Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1984-03-13
1985-04-16
Siegel, Alan
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549 71, A61K 3138, C07D33324
Patent
active
045115770
ABSTRACT:
A novel derivative of benzoic acid, 2-(2-thenoyloxy)-benzoic acid of formula (I) ##STR1## and pharmaceutically acceptable salts thereof with alkali and alkali-earth metals and with basic amino acids such as lysine, arginine and histidine are valuable antiinflammatory and analgesic agents.
They may be prepared by reacting acetylsalicylic acid with a reactive derivative of 2-thiophenecarboxylic acid.
The compounds of the invention may be formulated with conventional pharmaceutically acceptable carriers or diluents, to provide a pharmaceutical composition.
REFERENCES:
Vega, Chem. Abstr., 94:30556u, (1981).
Remington's Pharm. Sciences, 15th ed., (1975), pp. 1048, 1049.
Media Research s.r.l.
Siegel Alan
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