Derivatives of antibiotic tylosin

Details Derivatives of antibiotic tylosin Derivatives of antibiotic tylosin

1979-09-14

1981-05-19

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 4, A61K 3171, C07H 1708

Patent

active

042686652

ABSTRACT:
Derivatives of antibiotic tylosin of the formula ##STR1## wherein R.sub.1 is hydrogen or lower alkanoyl, A.sub.1 and A.sub.2 are groups of which one is R.sub.2 and the other is R.sub.3, and R.sub.2 and R.sub.3 are C.sub.2-6 alkanoyl, or a physiologically acceptable salt thereof, have enhanced antibacterial activity against macrolide antibiotic-resistant strains.

REFERENCES:
patent: 4017607 (1977-04-01), Inouye et al.
patent: 4092473 (1978-05-01), Okamoto et al.

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