Derivatives of 9,10-dihydroxy-1-(p-alkoxybenzyl)-perhydroisoquin

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

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C07D26500, C07D27300, C07D29500

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active

040523896

ABSTRACT:
The disclosed invention is to a compound of the formula: ##STR1## in which R.sup.2 is lower alkyl. These compounds are useful in the preparation of N-substituted-14-hydroxy-3-substituted morphinan derivatives which have been found to possess potent narcotic agonist or antagonist activity.

REFERENCES:
patent: 3466288 (1969-09-01), Hansen et al.
patent: 3775414 (1973-11-01), Monkovic et al.
patent: 3819635 (1974-07-01), Pachter et al.
patent: 3905956 (1975-09-01), Derieg et al.
patent: 3919237 (1975-11-01), Halder
Chem. Abst. 77, 56400(n) (1972) Elliott et al.

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