Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2009-08-18
2011-12-20
Solola, Taofiq A (Department: 1622)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C549S467000
Reexamination Certificate
active
08080582
ABSTRACT:
The present application discloses derivatives of 8-epiblechnic acid and use thereof in treating a disease related to endothelin receptor A or endothelin-1 (ET-1) over-expression, such as hypertension, cancer, atherosclerosis, and myocardial infarction.
REFERENCES:
patent: WO 2004/012651 (2004-02-01), None
Zhou et al., Effect and mechanism of salvianolic acid B in attenuating elevated portal pressure in a rat model of portal hypertension induced by endothelin-1, Zhong Xi Yi Jie He Xue bao, 5(1), pp. 61-64, Jan. 2007, Abstract only.
Orry et al., Modeling and Docking the Endothelin G-Protein-Coupled Receptor, Biophysical Journal, vol. 79, pp. 3083-3094, Dec. 2000, p. 30830p. 3091.
Chan Hardy
Chao Chung Faye
Soong Vallapa
Cheng Kent H.
ScinoPharm Taiwan Ltd.
Solola Taofiq A
VLP Law Group LLP
LandOfFree
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