Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-su

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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544 21, 544 26, 544 27, C07D50136, A61K 31545, C07D50160

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active

040667626

ABSTRACT:
New semisynthetic cephalosporins are described whose structures are characterized by having an .alpha.-oxyimino group in the 7-acetamido moiety and a sulfosubstituted tetrazolylthiomethyl group at position 3. The compounds are active antibacterial agents especially against Gram negative organisms.

REFERENCES:
patent: 3812110 (1974-05-01), Lee et al.
patent: 3966717 (1976-06-01), Cook et al.
patent: 3971778 (1976-07-01), Cook et al.
patent: 3974153 (1976-08-01), Cook et al.
Glaxo, Chemical Abstracts, (1974) vol. 81, Abstract 37,558m.
Ibid.
VOL. 81, Abstract 169,551p, (1974).
Ibid.
VOL. 83, Abst. 179,082s, (1975).
Ibid.
VOL. 83: 43,354Z (1975).
V. Morrison et al., Organic Chemistry, (1966), p. 707.

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