Derivatives of 5-pyridazinyl-1-azabicyclo[3.2.1]octane,...

Details Derivatives of 5-pyridazinyl-1-azabicyclo[3.2.1]octane,... Derivatives of 5-pyridazinyl-1-azabicyclo[3.2.1]octane,...

2008-12-05

2011-12-13

Fetterolf, Brandon (Department: 1628)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S238000

Reexamination Certificate

active

08076340

ABSTRACT:
The invention relates to compounds having general formula (I), wherein R is as defined herein.The invention also relates to acid addition salt, a hydrate or a solvate of compounds of formula (I). The invention further relates to the method of preparing said compounds and to the use of same in therapeutics.

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Maelicke (Dementia and Geriatic Cognitive Disorder Abstract only), vol. 11, suppl. 1, 2000.
ptcl.chem.ox.ac.uk/MSDS structure activity relationship; Jaworska, 1-8, 2004.
Holladay, M. W., et. al., Neuronal Nicotinic Acetylchloline Receptors as Targets for Drug Discovery, Journal of Medicnal Chemistry, vol. 40, No. 26, (1997) pp. 4169-4194.
Bourin, M., et al., Nicotinic Receptors and Alzheimer's Disease, Current Medical Research and Opinion, vol. 19, No. 3, pp. 169-177, (2003).

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