Derivatives of 5-androsten-17-ones and 5-androstan-17-ones

Details Derivatives of 5-androsten-17-ones and 5-androstan-17-ones Derivatives of 5-androsten-17-ones and 5-androstan-17-ones

1995-06-06

1998-09-08

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514178, 552536, 552624, 552650, 552651, 552652, A61K 3156, C07J 100, C07J 1100

Patent

active

058045767

ABSTRACT:
Steroids of the formula: ##STR1## useful as cancer preventive agents, anti-obesity agents, anti-hyperglycemic agents, anti-aging agents, and anti-hypercholesterolemic agents and anti-auto-immune agents.

REFERENCES:
patent: 2833793 (1958-05-01), Dodson et al.
patent: 2911418 (1959-11-01), Johns et al.
patent: 3018298 (1962-01-01), Klimstra et al.
patent: 3148198 (1964-09-01), Goldcamp
patent: 3166578 (1965-01-01), Klimstra et al.
patent: 3357888 (1967-12-01), Campbell et al.
patent: 3391166 (1968-07-01), Klimstra
patent: 3471480 (1969-10-01), Fritsch et al.
patent: 3471526 (1969-10-01), Klimstra
patent: 3580937 (1971-05-01), Campbell et al.
patent: 3976691 (1976-08-01), Middleton et al.
patent: 3983144 (1976-09-01), Leemhuis
patent: 4518595 (1985-05-01), Coleman et al.
patent: 4628052 (1986-12-01), Peat
patent: 4666898 (1987-05-01), Coleman et al.
patent: 4897390 (1990-01-01), Ruhe
patent: 4898694 (1990-02-01), Schwartz et al.
patent: 5001119 (1991-03-01), Schwartz et al.
patent: 5028631 (1991-07-01), Schwartz et al.
patent: 5157031 (1992-10-01), Schwartz et al.
Schwartz, Nutr Cancer, 3, 46-53 (1981).
Pashko, Chem. Abs. 101315K (1984).
Schwartz, et al., Chem Abs. 103, 123791m (1985).
Robinson, et al., J. Org. Chem. 28, 975-980 (1963).
Hanson, et al. Perkin Transactions I, 499-501 (1977).
Goldman, et al., Biochimica and Biophysica Acta, 233-249 (1973).
Pashko, et al., Carcinogenesis, 2, 717-721 (1981).
Abou-Gharbia et al., Journal of Pharmaceutical Sciences, 70, 1154 (1981).
Raineri and Levy, Biochemistry 9, 2233-2243 (1970).
Pelc, et al., Collection Czechoslov. Chem. Comm., 31, 1064 (1966).
Klimstra, et al., Journal of Med. Chem. 9, 924 (1966).
Bridgeman, et al., J. Chem. Soc., C, 250 (1970).
Mailloux, et al., Bulletin de la Societe Chemiqu de France, 617 (1969).
Catsoulacos, Chemical Abstracts 67, 54331K (1967).
Catsoulacos, et al., J. Org. Chem., 32, 3723-3724 (1967).
Sheppard, et al., J.C.S. Perkins I, 2551 (1977).
Crabb, et al., J.C.S. Perkins I, 1041 (1981).
Geoffrey Bird, et al., J.C.S. Perkins I, 750 (1980).
Kirk, et al., J.C.S. Perkins I, 762 (1976).
Evans, Chemical Abstracts 79, 42729 (1973).
Denny, et al., J.C.S. Perkins I, 486 (1972).
Chemical Abstracts 89, 105865g (1978).
Numazawa, et al., Steroids 32, 514-527 (1978).
Pashko, et al., Carcinogenesis 5, #4, 463-466 (1984).
Harrison's Principle of Internal Medicine, 350, (1983).
Chemical Abstracts 89, 10586b (1978).
Shoppe, et al., J.C.S. (C) 2767 (1969).
Bird, et al., Journal of Chemical Society, 1979, pp. 65-66.
Jones, et al., Journal of Chemical Society, Perkin Transactions I, 22, 1975, 2308-2312.
Wolf et al., J. Org. Chem. 41, No. 7, 1976, pp. 1254-1255.
Combe, et al., J.C.S., Series C, pp. 2300-2305 (1971).
Jones, et al., J.C.S., Series C, 2421-2426 (1970).
Labler, et al., Collection Czechoslov. Chem. Comm., 33, 2226-2237 (1968).
Chemical Abstracts 63, 11647-11648 (1965).
Ramseyer, et al., Steroids, 3347-3365 (1967).
Johnston, et al., J.C.S., Series C, 1847-1856 (1966).
Browne et al., J.C.S., Perkin Transactions I, pp. 1493-1499 (1973).
Chemical Abstracts 85, 5945b (1976).
Djerassi, Carl, "Steroid Reactions", p. 199 (1963).
"Chemical Abstracts 42", 11647f-11648g (1965).
Chemical Abstracts 85: 5945b (1976).
Boone, Cancer Research 50, 2-9 (1990).
Meyskens, New England J. Medincin vol. 323, p. 825 (1990).
Lippman et al, Journal of the NCl 82 p. 555 (1990).
Ratko, Cancer Research 51, 481 (1991).
Schwartz, et al. (1981), "Dehydroepiandrosterone: An Anti-Obesity and Anti-Carcinogenic Agent", Nutrition and Cancer, 3:46-53.
Rao, Cancer Research 51, 45 28 (1991).
Schwartz (1989) Carcinogenesis 10, 1809 (1989).
Boone (1992), Cancer Research 52, 1651 (1992).
Shantz, Proc. Natl. Acad. Sci 86, 3852 (1989).
Schwartz-1988 (Cancer Research 48, 4817g (1988).
Pashko, Carcinogenesis, 12, 2189 (1991).
Garcea, Carcinogenesis 9, 931 (1988).
Fels, Ann Report 1974-1980 p. 33.

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