Derivatives of 4-(thio- or...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S324000, C514S285000, C514S183000, C435S007200, C546S102000, C546S104000, C546S202000

Reexamination Certificate

active

07060711

ABSTRACT:
The present invention relates to derivatives of 4-(Thio- or Selenoxanthene-9-ylidene)-piperidine or acridine and pharmaceutically acceptable salts thereof, use of these compounds as a medicament and for the manufacture of a medicament for treatment of a disease state which can be alleviated by treatment with a 5-HT2B antagonist.

REFERENCES:
patent: 3275640 (1966-09-01), Engelhardt et al.
patent: 3408355 (1968-10-01), Renz et al.
patent: 3557287 (1971-01-01), Berde et al.
patent: 4285956 (1981-08-01), Lassen et al.
patent: 4777177 (1988-10-01), Traber et al.
patent: 22 56 392 (1973-05-01), None
patent: 0 005 607 (1979-11-01), None
patent: 2 290 202 (1976-06-01), None
patent: 1000509 (1965-08-01), None
patent: 42137 (1980-06-01), None
Kaiser, C. et al.: Analogs of phenothiazines. Synthesis and neuropharmacological activity of some piperidylidene derivatives of Thioxanthenes, Xanthenes, Dibenzoxepins and Acridans. J. Med. Chem. vol. 17, pp. 57-62, 1974.

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