Derivatives of 4-phenyl quinazoline active on the central nervou

Details Derivatives of 4-phenyl quinazoline active on the central nervou Derivatives of 4-phenyl quinazoline active on the central nervou

1982-10-19

1985-02-12

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544283, 544292, A61K 31505, C07D23984

Patent

active

044990928

ABSTRACT:
The present invention relates to novel derivatives of 4-phenyl quinazoline of general formula: ##STR1## in which R.sub.2 is H or halogen or R.sub.1 is a hydroxyamino derivative of type ##STR2## in which at least R.sub.3 or R.sub.4 comprises an OH group or ##STR3## in which R.sub.5 comprises an OH group or ##STR4## it also relates to the drugs which may be used as minor tranquilizers, hypnotics and antiepileptics containing a product of formula (I).

REFERENCES:
patent: 3305553 (1967-02-01), Hoefle et al.
patent: 3509141 (1970-04-01), Walker
patent: 4183932 (1980-01-01), Yamamoto et al.
Walker, "Chemical Abstracts", vol. 73, 1970, Col. 3927a.
Shenoy, "Chemical Abstracts", vol. 84, 1976, Col. 84:90191z.
Yamamoto, et al., "Chemial Abstracts", vol. 89, 1978, Col. 89:43488u.
Yamamoto, et al., "Chemical Abstracts", vol. 89, 1978, Col. 197593n.

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