Derivatives of 4-phenyl-4-oxo-2-butenoic acid their preparation

Details Derivatives of 4-phenyl-4-oxo-2-butenoic acid their preparation Derivatives of 4-phenyl-4-oxo-2-butenoic acid their preparation

1988-06-21

1989-09-19

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

560 53, C07C 5990

Patent

active

048677370

ABSTRACT:
Compounds of the formula (I): ##STR1## in which R.sub.1 represents alkoxy containing from 1 to 8 carbon atoms, and R represents hydrogen or alkyl containing from 1 to 8 carbon atoms, as well as their alkali metal, alkaline-earth metal, ammonium or amine salts, which are useful in the treatment of hyperchlorhydria, gastric or gastroduodenal ulcers, gastritis, hiatal hernias, or gastric or gastroduodenal ailments accompanied by gastric hyperacidity. Also, therapeutic compositions containing the same and method of treating patients suffering from these ailments.

REFERENCES:
patent: 4450292 (1984-05-01), Christidis
patent: 4454155 (1984-06-01), Christidis
patent: 4594443 (1986-06-01), Bianchi

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