Derivatives of 3-guanidinocarbonyl-1-heteroaryl-pyrrole,...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S422000, C514S426000, C546S167000, C549S517000, C549S518000

Reexamination Certificate

active

07078414

ABSTRACT:
The present invention relates to 3-guanidinocarbonyl-1-heteroaryl-pyrrole derivatives of formula (I) wherein R1to R3and Ar are as defined herein, pharmaceutical compositions comprising such derivatives, methods of treatment comprising administering such derivatives, and processes for their preparation

REFERENCES:
patent: 5698581 (1997-12-01), Kleemann
patent: WO 94/26709 (1994-11-01), None
patent: WO 99/43663 (1999-09-01), None
Guzman—Perez et al, Discovery of Zoniporide: A Potent and Selective Sodium-Hydrogen Exchanger Type 1 (NHE-1) Inhibitor with High Aqueous Solubility, Bioorganic & Medicinal Chemistry Letters vol. 11; No. 6: (2001); pp. 803-807.

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